Men with ED often develop performance anxietydue to the stressors of not being able to achieve or maintain an erection. Fortunately, patients don’t have to live with the condition as it can be treated with medication like Sildenafil. Besides being affordable Sildenafil also contains a potent active ingredient, sildenafil citrate which along with the tablets natural MOA helps patients combat ED and regain their sexual lives.
The tablet has a balanced set of benefits which range from a quick acting formula and long-lasting results to an impressive tolerability and safety profile. Patients are encouraged to remember that Sildenafil is bioequivalent to Viagra thus it mirrors Viagra’s effects and results which makes it the best generic Viagra (same tolerance but lower price).
How Effective Is Sildenafil in Treating ED?
Sildenafil is known to be extremely effective to prove this an extensive study was conducted. This study included 1200 menwho were some were given a100mg dose ofSildenafil, while others were given a placebo.
The results of the study are as follows:
· 57% of the men who took Sildenafil 100mg reported improved, firm erections 30 minutes after ingesting the medication, as compared to those who took the placebo (21%).
· 83% of the men reported feeling more confident about themselves and in satisfying their partner.
· 85% of the men reported no side effects, 15% of the men felt common side effects but it went away on their own or was well-managed.
The study proves that this treatment is the best generic Viagra in improving erectile function and is very well-tolerated by the participants. Sildenafil clearly has a greater impact than placebo on the participants of the study.
MOA: How Does Sildenafil Work - So Flawlessly?
Once consumed Sildenafil works to block the PDE5 enzyme. PDE5 is responsible for blood flow and restriction thus it plays a vital role in the process of an erection.Smooth muscle tissue and blood vessels which line the penis contain high concentrations of PDE5, which stops another molecule called cGMP, and subsequently reduces nitric oxide production.
Nitric oxide is essential for erections to occur, as this substance relaxes the blood vessels and contributes to blood flow. When Sildenafil’s main ingredient, sildenafil citrate is activated in the body, PDE5 secretion is inhibited which encourages the production of cGMP. This boosts the production of nitric oxide and leads to a firm erection.
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